JAMES XUE , Ph.D. , M.B.A.
FOUNDER , CHAIRMAN AND CEO
Dr. James Xue is a veteran entrepreneur with extensive experience spans from US to China and from small biotech to multi-national biopharmaceutical companies. Over the last two decades, Dr. Xue led or was involved in several start-up companies and situations as well as managed sizable business and operations that contributed to his unique insight and deep knowledge in the biotech industry.
Dr. Xue built his biotech career by working for some of world’s most innovative companies in the San Francisco Bay Area and the Boston Area. Prior to CANbridge, he was a senior executive at Genzyme where he spent 10 years in various managerial positions with increasing responsibilities. For five years he was founding general manager of Genzyme China during which he managed the launch of several life-saving drugs for the treatment of hematologic cancer and rare metabolic diseases in China including Thymoglobuline® and Cerezyme®. Dr. Xue was recognized as a distinguished expert entrepreneur by the “the Recruitment Program of Global Experts”.
Dr. Xue holds a B.S. in Pharmaceutical Chemistry from Peking University School of Pharmacy, a Ph.D. in Bioorganic Chemistry from Brown University and a M.B.A. from Darden School of Business, University of Virginia. He received executive training from INSEAD and Wharton Business School. Dr. Xue is a R & D Committee Member of China Pharmaceutical Innovation and Research Development Association (PHIRDA), a member of the Advisory Committee of the Joint Institute of Peking University Health Science Center and University of Michigan Medical School. He is a member of BayHelix Group and founding member of BayHelix Boston Chapter.
CHIEF FINANCE OFFICER & CHIEF BUSINESS OFFICER
Glenn brings more than 15 years of experience in the healthcare sector globally, as an investor, investment banker, and strategy consultant. Before joining CANbridge Glenn was Director, Healthcare Investment Banking at China Renaissance, where he advised Greater China and US life science companies on cross-border M&A and capital raising activities. Prior to this, Glenn spent more than a decade investing in the healthcare sector globally. Most recently, he was Senior Analyst and Portfolio Manager at Leerink Capital. Before Leerink, Glenn was Senior Analyst at Citadel’s Surveyor Capital, its global equity long/short multi-manager strategy and Senior Healthcare Specialist, at Fidelity Investments, where he contributed to the global healthcare research effort for the overall Fidelity funds complex and supported the growth of the Fidelity healthcare team’s dedicated assets.
His professional experience also includes strategy consulting and M&A investment banking. Glenn received a Bachelor of Science in Business with a finance concentration from Indiana University and a Master of Science in Global Finance Analysis from Bentley University’s McCallum Graduate School of Business, where he graduated with High Distinction.
CHIEF DEVELOPMENT STRATEGIST & INTERIM CHIEF MEDICAL OFFICER
Prior to founding his consulting practice, Dr. Cox was Chief Medical Officer for Editas Medicine, in Cambridge, where he led the clinical development of CRISPR-based genome editing medicines to treat human diseases, resulting in the first IND approval for in vivo delivery of CRISPR/Cas9 gene editing. Dr. Cox also had a long stint at Sanofi Genzyme, also in Cambridge, culminating as Vice President, Rare Disease Clinical Development, where he oversaw multiple global rare disease clinical development programs, including Cerdelga®; olipudase alfa; Hectoral®; Cerezyme®, and Aldurazyme®, as well as Elaprase® in Asia, among others. Before then, Dr. Cox held several senior medical R&D positions at Genzyme and was the company’s first clinical geneticist recruited to oversee human clinical development programs for rare genetic diseases.
Dr. Cox is a board-certified clinical geneticist and pediatrician who trained at Boston Children’s Hospital, where he remains on staff and continues to see patients with genetic diseases. He earned an MD and PhD in Biology from the University of California at San Diego, and a Bachelor of Arts in Biology, from Harvard College. He holds multiple patents and awards and has authored scores of peer-reviewed publications, presentations and book chapters.
SENIOR VICE PRESIDENT, RARE DISEASE COMMERCIAL OPERATIONS
Mr. Cheresky has nearly 20 years’ business leadership experience in the biotechnology industry. Most recently, he was Vice President, Emerging Markets at Bioverativ, a Sanofi company, in Boston, MA, where he established regional structures for emerging markets and oversaw country launches in multiple emerging markets, including Australia, Columbia and Taiwan. Before then, Mr. Cheresky was Executive Director, Routes -to-Care Strategy, Ultragenyx Pharmaceuticals, in Novato, CA, where he developed a strategy for improving patient treatment access and provided direction to the medical field team. Prior to that, he was Regional Vice President – Latin America, for Synageva Biopharma, in Boston, MA, responsible for all Latin American operations, including clinical trial programs and regulatory affairs in Brazil, Argentina, Colombia and Mexico, where he oversaw the regulatory submission and approval for Kanuma®. Mexico was the third country to gain Marketing Authorization for Kanuma® worldwide. Earlier, Mr. Cheresky held multiple international positions at Genzyme Corporation, in Boston, MA
Mr. Cheresky holds a Master of Business Administration, from the University of North Carolina Kenan-Flagler Business School, Chapel Hill, and Bachelor of Science, Marketing, from the Universidad Argentina de la Empresa, Buenos Aires, Argentina.
CHINA CHIEF MEDICAL OFFICER
Dr. Annie Teng has a strong background in oncology and rare disease. Most recently, she was Head of Biology & Early Development at Sanofi, after having served for six years as Medical Director, Specialty Care, there. Prior to Sanofi, she was at Bristol-Meyer-Squibb China, where she was Disease Area Head for Oncology and Immunology. Dr. Teng also spent time in oncology at Pfizer & Pharmacia (later acquired by Pfizer), and started her medical career in pediatrics, focusing on hematology, at Chinese PLA Hospital for 11 years.
Dr. Teng earned her Medical and Master’s degree in Pediatric Medicine from China Medical University. Dr. Teng has also received multiple workplace awards throughout her career, including: China R&D President Award and China Medical Golden Award, both from Sanofi, and the President’s Special Award and Asia-Pacific Award, from BMS.
VICE PRESIDENT OF REGULATORY AFFAIRS AND QUALITY
Ms. Zhang brings to the position considerable regulatory experience in China in oncology and rare diseases. Prior to join CANbridge, she was the Head of Regulatory Affairs at Novartis Oncology China, where she focused on hematology, solid tumors, and rare diseases. Under her leadership, Novartis Oncology secured six New Drug Applications (NDA) from the China FDA (CFDA). Additionally, Ms. Zhang provided regulatory support for the maintenance and growth of 15 oncology products, and grew the team from 5 to 14 people. She was also a key contributor to the Novartis oncology pipeline development and regulatory strategy in China. From 2012 to 2017, Ms. Zhang served on the R&D-based Pharmaceutical Association Committee (RDPAC), a key Chinese pharmaceutical industry association, as Chair of the Orphan Drug Task Force, where she worked closely with the CFDA on regulation development for orphan drugs. In 2015 and 2017, Ms. Zhang was a speaker at China Rare Disease Summit.
Prior to Novartis, Ms. Zhang was Associate Director of Regulatory Affairs at Genzyme China, where she is the head of the regulatory affairs and focused on rare diseases. Before then, she worked in regulatory affairs at several companies, including Shanghai Roche and Sanofi China. Ms. Zhang started her career as a researcher in the Department of Pharmaceutical Analysis, National Institutes of Pharmaceutical Research & Development, SFDA.
Ms. Zhang holds a MA in Clinical Pharmacology from Hebei Medical University in Shijiazhuang city, China, and a BS in Pharmaceutics from China Pharmaceutical University, in Nanjing, China. She is also a licensed pharmacist.
VICE PRESIDENT OF CHINA COMMERCIAL OPERATIONS
Lisa Li is a seasoned leader in the pharmaceutical industry in China with comprehensive knowledge and rich experience in sales and marketing. She comes to CANbridge directly from AbbVie, where she held several positions. Most recently, she was Commercial Director for Rheumatology, Japan-Asia Pacific Region at AbbVie, where she was responsible for driving the regional strategy of the Rheumatology franchise for Humira and ensuring Upadacitinib launch readiness in top markets such as Japan, Australia, Taiwan, Korea and China. Prior to this, she was the Business Unit Director for Immunology in China where she was instrumental in improving the strategies, planning and processes to build an effective business unit and drive business growth. Prior to AbbVie, Lisa held a variety of positions of increasing responsibility, including Marketing & Sales Director in Biogen Idec China; Marketing Director, Oncology with Eli Lilly China and Marketing Manager at Merck Sharp & Dohme Corp. where she gained valuable global marketing experience focusing on new pipeline products launching strategy in hematology malignancy in the US headquarter. She had successfully led several new product/indications launches in China including Cellcept for kidney transplantation, Gemzer in breast cancer, Alimita in non-small cell lung cancer, and recently Humira in treating psoriasis patient.
Lisa obtained her bachelor degree of medicine from Shanghai Jiao Tong University. In 2002, she received her Master of International Business from the University of Auckland.
VICE PRESIDENT OF FINANCE AND CONTROLLER
Jeff brings with him 23 years of extensive experience in pharmaceutical finance management and operations. Prior to joining CANbridge, he was with Sanofi China for 5 years and most recently Senior Director, Head of Business Controlling, China Pharma & CHC at Sanofi China. His responsibilities covered 6 BUs with combined revenues of 2 billion euros and a team with 20 staffs. Between 2013 and 2016, He was Pharma Controlling Director and responsible for P&L and OPEX driven financial performance, operations, planning, budgeting, forecasting and reporting, control and compliance. As the China pharma finance lead with a team of 15 staffs, Jeff partnered with country GM and BU heads，implemented systems and processes to ensure business growth and provided decision support. Prior to Sanofi, Jeff built his solid career in pharmaceutical finance at GSK for almost 18 years. He started as Assistant Account at Glaxo Wellcome (which became GSK after the merger between Glaxo Wellcome and SmithKline Beechem in 2001) Hong Kong in 1995. Over the years he progressed his career in financial accounting, FP&A, reporting and operations with increasing responsibilities spanning from GSK Hong Kong to GSK China. His last role at GSK was Senior Finance Manager for GSK China, where he led the Finance Business Partner Team and supported 6 Rx Business Units and Hong Kong with combined revenues of around 800M euros in 2012.
Jeff holds a bachelor’s degree in Business Administration with a major in Accounting from University of Wisconsin, Madison in the U.S. He is also a Certified Public Accountant (Member of AICPA and HKICPA).
EXECUTIVE DIRECTOR OF CLINICAL OPERATIONS
Anna has 20 years in pharmaceutical industry and 14+ years’ experience in pharmaceutical R&D department. Prior to CANbridge, Anna worked as Senior Director in JIANGSU HengRui Medicine Co., LTD, who led one PM team with expertise accelerated in its key oncology pipeline. She worked as senior manager-business operations focused on resource management and vendor management including quality and bidding in Boehringer Ingelheim. She accelerated comprehensive study management skills working as Clinical Development Manager at China Clinical Operations Hub in AstraZeneca, a global R &D function. She led the delivery of all components of a clinical study to time, cost, and quality from Study Specifications (SS) through study closeout activities and Clinical Study Report (CSR) for regional trials, China registration trials and Phase I trials.
She holds Master Degree of Clinical Medicine from Shanghai University of Traditional Chinese Medicine.
SENIOR DIRECTOR OF HUMAN RESOURCES
Chris has over 17 years of bio-pharmaceutical experience in HR management in an all-round way, including 11 years of professional experience in Human Resource Management of a US listed company. Prior to joining CANbridge, Chris held several HR management positions at Sinovac Biotech Ltd. (Nasdaq GSM: SVA) , she has rich experience on recruiting , and in charge of other important HR functions. During those 11 years, staff member increased from 25 to more than 600. Sinovac developed from one single company to a Group, with several subsidiary companies and JV companies. Prior to CANbridge, Chris was the HR Director of Huadu Biotech Ltd.
Chris graduated with a Master Degree in Human Resource Management from RenMin University of China.
Charles Feng accelerated 20+ years’ experience in R&D and management positions in pharmaceutical industry. Before joined CANbridge, he worked as lecturer in the Fourth Military Medical University. He stepped into industry as CMC director at Jiangsu Pacific Minock Biopharmaceutical Co., Ltd. and technical director of Tiger Med Co Ltd.
He led key projects of CMC development for innovative drugs, local technical transfer, production of clinical stage supply and worked as core member for IND/ NDA submission. He oversaw the whole process of upstream and downstream development, GMP production management and overall project management of bio-logical drugs.
He was involved in 863 major national science and technology projects and other key international collaborative projects when working in institution. He has authored scores of papers and book chapters.
Charles holds doctorate degree in cell biology from the Fourth Military Medical University of the Chinese People's Liberation Army.
HEAD OF MARKET ACCESS
Lily brings with her 17 years of market access experience with a proven track record across multiple therapeutic areas at global pharmaceutical companies. Prior to joining CANbridge, she was Head of Central Market Access, Oncology & Rare Disease Products at Novartis China. She provided leadership and operational oversight to address product value to payer and obtain their recognition in preparations Revolade, Jakavi and Exjade for the 2019 NRDL negotiation that is still ongoing. She played a key role in execution of the negotiation of NRDL listing of Tasigna, Zykadia, Votrient and Sandostatin LAR, contributing to significant revenue growth. Before Novartis, she was with Novo Nordisk China for 7 years most recently as Associated Director of Innovative Access and Market Access Operations. She led a successful campaign that resulted in the listing of Victoza in 2017 NRDL and no significant price cut of NovoSeven. She was able to create a PRDL window for Novo products in Tianjin by leveraging Novo’s manufacturing facility locally. In her earlier professional years Lily held various positions in market access and medical information and government affairs at GSK, Pfizer, Novartis and Xi’an Janssen.
Lily obtained her bachelor’s degree in marketing and sales from North East University.
Strategic Advisory Board
MICHAEL J. GLYNN, M.B.A.
Mike Glynn is a seasoned global executive with over 40 years of general management and commercialization experience in Asia Pacific, Japan, Middle East, Latin America and the United States. He has an impressive track record in start-up, turnaround, rapid growth, and organizational development situations.
His employment experience includes three years as SVP Global Commercial Operations at Synageva prior to its acquisition by Alexion; one year as EVP and Chief Commercial Officer at Pacific Biosciences; five years as SVP and Regional President Japan and Asia Pacific at Genzyme; seven years at Boston Scientific, two as Division President of Endovations, one as VP and General Manager Asia, Middle East and Turkey, and four as VP and General Manager Asia Pacific. Earlier in his career he spent 10 years at Baxter International in various functional management roles in Australia and the United States.
At Genzyme, Mike was responsible for the overall P & L and direction of Genzyme’s business in Japan-Asia Pacific with over $500 million in sales and over 600 employees. Revenues grew from $186 million in 2007 to just over $500 million in 2011 with a similar growth in profits. At Boston Scientific he was responsible for approximately $200 million in sales and 420 employees in Asia. During his tenure sales increased at a compounded annual growth rate of just over 30% and operating income increased at a CAGR of 182%.
Mike has a MBA from Macquarie University, Australia and a B.Sc. and Diploma in Education from the National University of Ireland.
Mr. Geraghty is an industry leader with 30 years of strategic and leadership experience, including more than 20 years as a senior member of executive teams at biotechnology companies developing and commercializing innovative therapies. Mr. Geraghty previously served as Senior Vice President, North America Strategy and Business Development at Sanofi, which he joined upon its acquisition of Genzyme. Mr. Geraghty spent 20 years at Genzyme, where his roles included Senior Vice President International Development, President of Genzyme Europe, and General Manager of Genzyme's cardiovascular business. Mr. Geraghty also oversaw Genzyme's Humanitarian Assistance for Neglected Diseases (HAND) program, under which the company supported innovative development programs on a non-commercial basis. Mr. Geraghty is Chairman of the Board of Idera Pharmaceuticals and Pieris Pharmaceuticals and serves on the Board of Voyager Therapeutics and Fulcrum Therapeutics. He is also a member of the BIO Ventures for Global Health Board of Directors. He started his career in healthcare strategy consulting at Bain and Company.
A graduate of the Yale Law School, Mr. Geraghty holds a M.S. from the University of Pennsylvania and a B.A. from Georgetown University.
Iain Baird has worked in the pharmaceutical industry for 29 years. He started work for ICI which later became Zeneca and then AstraZeneca. An engineer by discipline he initially designed and project managed the building of pharmaceutical facilities before moving into operational management running multiple production facilities in the United Kingdom. Since 2003 he has worked in the USA and was part of the leadership team that established the Avecia Oligonucleotides business as a CMO, taking a small team of researchers and growing it into an FDA approved manufacturing site with 150 employees’. In 2006 Iain was one of the principles that established Avecia Vaccines in which he led the manufacturing and supply groups in the development of vaccines against anthrax and plague.
Since 2010 Iain has been an independent consultant assisting clients in the development of their clinical products and has been involved in 3 successful BLA applications and 3 NDA applications as well as remediating a product placed on CMC hold by the FDA. Iain has supported clients through numerous FDA, EMA and international regulatory inspections, preparing them for the inspections, supporting them during the inspections and in their successful responses.
Iain specializes in working with the founders/CEO’s of companies with innovative products and services and has been working with CANbridge CEO James Xue since the start of 2013 assisting in the evaluation of product candidates that could be developed in the Chinese market. During that time, Iain has also worked with the founder of Gallus in the negotiation and establishment of Gallus Biopharmaceuticals, a pure play CDMO, and subsequently has worked with the founder of Brammer Bio for the development and manufacturing of viral vectors.
XIAOPING YE , M.D. , Ph.D.
Founder, President of Tigermed, M.D., Ph.D., E.M.B.A.
EMBA of Guanghua School of Management, Peking University, obtained PhD in Oxford University UK.
Over 10 years’ experience in medical and regulatory affairs with global pharmaceutical industries.
The Former medical director in Shanghai Roche for 6 years.
MARK GOLDBERG , M.D.
Dr. Goldberg joined CANbridge as Acting Chief Medical Officer in 2015. He has been a member of the company's Advisory Board since 2013. Dr. Goldberg brings to CANbridge over 30 years of clinical and industry experience as a seasoned oncologist, hematologist and corporate medical/regulatory strategist.
Prior to CANbridge, he was Executive Vice President, Medical and Regulatory Strategy at Synageva BioPharma Corporation. Dr. Goldberg joined Synageva in 2011 from Genzyme Corporation, where he had most recently served as Senior Vice President, Clinical Development and Global Therapeutic Group Head, Oncology and Personalized Genetic Health. While at Genzyme, he played a central role in the development and approval of medicines such as Fabrazyme®, Aldurazyme®, Myozyme®, Lumizyme®, and Mozobil®. Prior to working at Genzyme, he was a full-time staff physician at Brigham and Women's Hospital and Dana Farber Cancer Institute. He holds appointments at Brigham and Women's Hospital and Dana Farber Cancer Institute and is also an Associate Professor of Medicine (part time) at Harvard Medical School.
Dr. Goldberg received his A.B. (magna cum laude) from Harvard College and his M.D. (cum laude) from Harvard Medical School. He holds Board appointments at Immunogen Corporation, Idera Pharmaceuticals, Glycomimetics, aTyr Pharma, Blueprint Medicines, and the American Cancer Society, New England Division.